TABLE 1

Characteristics of control (db/+), type 2 (db/db), and type 1 (STZ-administered db/+) diabetic mice; body weights and dry heart weights; and plasma levels of glucose, free fatty acids, triglycerides, and insulin at time of death

MiceBody weight (g)Heart dry weight (mg)Glucose (mmol/l)Fatty acids (mmol/l)Triglycerides (mmol/l)Insulin (μg/l)
db/+28.3 ± 0.730.5 ± 1.011.2 ± 0.40.51 ± 0.040.68 ± 0.071.20 ± 0.21
db/db47.0 ± 0.8*27.6 ± 0.432.2 ± 1.6*1.03 ± 0.08*0.89 ± 0.094.77 ± 0.83*
STZ21.5 ± 0.6*22.0 ± 0.4*31.8 ± 1.8*0.45 ± 0.060.57 ± 0.090.25 ± 0.04*
  • Data are means ± SE. n = 15–19, and n = 6–11 for the insulin values.

  • *

    * P < 0.05 vs. db/+.