TABLE 1

Apoptotic rates in pancreatic tissue sections from mouse models of diabetes, as determined by annexin V Cy5.5 and TUNEL staining

Annexin V Cy5.5TUNEL
Type 1 diabetes
    STZ treated
        MLDS2.3 ± 0.21.6 ± 0.2
        SHDS26.3 ± 0.817.5 ± 0.6
    NOD
        3-week-old NOD00
        6-week-old NOD00.6 ± 0.1
        8-week-old NOD2.6 ± 0.31.2 ± 0.2
        12-week-old NOD3.2 ± 0.22.3 ± 0.3
Type 2 diabetes
    db/db2.3 ± 0.32.0 ± 0.1
  • Data are means ± SE (%).