TABLE 1

Anthropometric and laboratory measurements before and after pioglitazone treatment for 16 weeks

BeforeAfterP value
Body weight (kg)83.0 ± 3.086.0 ± 3.0<0.001
BMI (kg/m2)29.4 ± 1.130.4 ± 1.1<0.001
HbA1c (%)7.8 ± 0.46.7 ± 0.3<0.001
Fasting plasma glucose (mmol/l)10.0 ± 0.77.5 ± 0.6<0.001
Fasting plasma insulin (pmol/l)66 ± 1236 ± 6<0.01
Fasting plasma FFA (μmol/l)699 ± 57571 ± 55<0.01
Total cholesterol (mg/dl)203 ± 9195 ± 8
LDL cholesterol (mg/dl)125 ± 8123 ± 7
HDL cholesterol (mg/dl)45 ± 347 ± 4
Triglycerides (mg/dl)163 ± 23124 ± 170.02
AST (IU/l)27 ± 222 ± 10.01
ALT (IU/l)28 ± 322 ± 20.02
  • Data are mean ± SE. AST, aspartate transaminase (normal range, 13–47 IU/l); ALT, alanine transaminase (normal range, 5–40 IU/l).