Table 1

Subject characteristics

Healthy-weight subjects (n = 15)Obese subjects (n = 11)
Age (years)66.7 ± 1.166.4 ± 1.8
Height (cm)176 ± 2175 ± 2
Weight (kg)72.8 ± 2.097.7 ± 3.6***
BMI (kg · m−2)23.4 ± 0.331.9 ± 1.1***
Body fat mass (%)22.7 ± 1.536.4 ± 1.0***
Diastolic blood pressure (mmHg)83 ± 184 ± 2
Systolic blood pressure (mmHg)131 ± 2141 ± 2**
Total blood cholesterol concentration (mmol · L−1)5.8 ± 0.3 (n = 12)6.5 ± 0.4 (n = 8)
Fasting blood glucose concentration (mmol · L−1)4.68 ± 0.154.81 ± 0.19
Fasting serum insulin concentration (mU · L−1)5.2 ± 0.210.1 ± 1.8**
Serum C-reactive protein concentration (µg · mL−1)0.69 ± 0.094.20 ± 0.83***
Plasma adiponectin concentration (ng · mL−1)11.6 ± 1.16.7 ± 1.2**
Plasma IL-6 concentration (pg · mL−1)0.84 ± 0.161.98 ± 0.29**
Plasma leptin concentration (ng · mL−1)2.35 ± 0.319.58 ± 1.15***
Plasma resistin concentration (ng · mL−1)4.93 ± 0.346.43 ± 0.49*
Plasma TNF-α concentration (pg · mL−1)1.21 ± 0.202.28 ± 0.47*
MedicationsAspirin 75 mg daily (n = 1)Atenolol 50 mg daily (n = 1); aspirin 75 mg daily (n = 1); lisinopril 40 mg daily; Germoloids cream as required (n = 1)
  • Values are provided as mean ± SEM. ***P < 0.001, **P < 0.01, *P < 0.05, significantly different from healthy-weight subjects.