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Table of Contents

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September 01 2018; volume 67 issue 9

In This Issue

  • Open Access
    In This Issue of Diabetes
    Diabetes 2018 Sep; 67 (9): 1699-1700. https://doi.org/10.2337/db18-ti09
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ADA Award Lecture

  • Open Access
    Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture
    Domenico Accili
    Diabetes 2018 Sep; 67 (9): 1701-1709. https://doi.org/10.2337/dbi18-0025
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Perspectives in Diabetes

  • Open Access
    The Ascending GLP-1 Road From Clinical Safety to Reduction of Cardiovascular Complications
    Daniel J. Drucker
    Diabetes 2018 Sep; 67 (9): 1710-1719. https://doi.org/10.2337/dbi18-0008
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  • Open Access
    Targeting FXR and FGF19 to Treat Metabolic Diseases—Lessons Learned From Bariatric Surgery
    Nadejda Bozadjieva, Kristy M. Heppner and Randy J. Seeley
    Diabetes 2018 Sep; 67 (9): 1720-1728. https://doi.org/10.2337/dbi17-0007
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  • Open Access
    Microvascular Dysfunction and Hyperglycemia: A Vicious Cycle With Widespread Consequences
    Coen D.A. Stehouwer
    Diabetes 2018 Sep; 67 (9): 1729-1741. https://doi.org/10.2337/dbi17-0044
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Commentaries

  • Open Access
    A New Activator of Hepatocyte CaMKII in Fasting and Type 2 Diabetes
    Lale Ozcan and Ira Tabas
    Diabetes 2018 Sep; 67 (9): 1742-1744. https://doi.org/10.2337/dbi18-0026
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  • Open Access
    Intermittent Fasting and Prevention of Diabetic Retinopathy: Where Do We Go From Here?
    Martin Haluzík and Miloš Mráz
    Diabetes 2018 Sep; 67 (9): 1745-1747. https://doi.org/10.2337/dbi18-0022
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Metabolism

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    Prostaglandin F2α Facilitates Hepatic Glucose Production Through CaMKIIγ/p38/FOXO1 Signaling Pathway in Fasting and Obesity
    Yuanyang Wang, Shuai Yan, Bing Xiao, Shengkai Zuo, Qianqian Zhang, Guilin Chen, Yu Yu, Di Chen, Qian Liu, Yi Liu, Yujun Shen and Ying Yu
    Diabetes 2018 Sep; 67 (9): 1748-1760. https://doi.org/10.2337/db17-1521
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    Insulin Regulates Lipolysis and Fat Mass by Upregulating Growth/Differentiation Factor 3 in Adipose Tissue Macrophages
    Yun Bu, Katsuhide Okunishi, Satomi Yogosawa, Kouichi Mizuno, Maria Johnson Irudayam, Chester W. Brown and Tetsuro Izumi
    Diabetes 2018 Sep; 67 (9): 1761-1772. https://doi.org/10.2337/db17-1201
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Obesity Studies

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    Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21
    Teayoun Kim, Shelly Nason, Cassie Holleman, Mark Pepin, Landon Wilson, Taylor F. Berryhill, Adam R. Wende, Chad Steele, Martin E. Young, Stephen Barnes, Daniel J. Drucker, Brian Finan, Richard DiMarchi, Diego Perez-Tilve, Matthias Tschöp and Kirk M. Habegger
    Diabetes 2018 Sep; 67 (9): 1773-1782. https://doi.org/10.2337/db17-1502
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Islet Studies

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    Pseudotime Ordering of Single Human β-Cells Reveals States of Insulin Production and Unfolded Protein Response
    Yurong Xin, Giselle Dominguez Gutierrez, Haruka Okamoto, Jinrang Kim, Ann-Hwee Lee, Christina Adler, Min Ni, George D. Yancopoulos, Andrew J. Murphy and Jesper Gromada
    Diabetes 2018 Sep; 67 (9): 1783-1794. https://doi.org/10.2337/db18-0365
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    Inhibition of SNAT5 Induces Incretin-Responsive State From Incretin-Unresponsive State in Pancreatic β-Cells: Study of β-Cell Spheroid Clusters as a Model
    Mahira Hashim, Norihide Yokoi, Harumi Takahashi, Ghupurjan Gheni, Oduori S. Okechi, Tomohide Hayami, Naoya Murao, Shihomi Hidaka, Kohtaro Minami, Akira Mizoguchi and Susumu Seino
    Diabetes 2018 Sep; 67 (9): 1795-1806. https://doi.org/10.2337/db17-1486
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    The Dysregulation of the DLK1-MEG3 Locus in Islets From Patients With Type 2 Diabetes Is Mimicked by Targeted Epimutation of Its Promoter With TALE-DNMT Constructs
    Vasumathi Kameswaran, Maria L. Golson, Mireia Ramos-Rodríguez, Kristy Ou, Yue J. Wang, Jia Zhang, Lorenzo Pasquali and Klaus H. Kaestner
    Diabetes 2018 Sep; 67 (9): 1807-1815. https://doi.org/10.2337/db17-0682
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Immunology and Transplantation

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    Humanized Mouse Model to Study Type 1 Diabetes
    Sandrine Luce, Sophie Guinoiseau, Alexis Gadault, Franck Letourneur, Bertrand Blondeau, Patrick Nitschke, Eric Pasmant, Michel Vidaud, François Lemonnier and Christian Boitard
    Diabetes 2018 Sep; 67 (9): 1816-1829. https://doi.org/10.2337/db18-0202
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    Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice
    Javier A. Carrero, Nicholas D. Benshoff, Kimberly Nalley and Emil R. Unanue
    Diabetes 2018 Sep; 67 (9): 1830-1835. https://doi.org/10.2337/db18-0331
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    CD4 T Cells Reactive to Hybrid Insulin Peptides Are Indicators of Disease Activity in the NOD Mouse
    Rocky L. Baker, Braxton L. Jamison, Timothy A. Wiles, Robin S. Lindsay, Gene Barbour, Brenda Bradley, Thomas Delong, Rachel S. Friedman, Maki Nakayama and Kathryn Haskins
    Diabetes 2018 Sep; 67 (9): 1836-1846. https://doi.org/10.2337/db18-0200
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Pathophysiology

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    Inhibition of Epidermal Growth Factor Receptor Activation Is Associated With Improved Diabetic Nephropathy and Insulin Resistance in Type 2 Diabetes
    Zhilian Li, Yan Li, Jessica M. Overstreet, Sungjin Chung, Aolei Niu, Xiaofeng Fan, Suwan Wang, Yinqiu Wang, Ming-Zhi Zhang and Raymond C. Harris
    Diabetes 2018 Sep; 67 (9): 1847-1857. https://doi.org/10.2337/db17-1513
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    Loss of IDO1 Expression From Human Pancreatic β-Cells Precedes Their Destruction During the Development of Type 1 Diabetes
    Florence Anquetil, Giada Mondanelli, Nathaly Gonzalez, Teresa Rodriguez Calvo, Jose Zapardiel Gonzalo, Lars Krogvold, Knut Dahl-Jørgensen, Benoit Van den Eynde, Ciriana Orabona, Ursula Grohmann and Matthias G. von Herrath
    Diabetes 2018 Sep; 67 (9): 1858-1866. https://doi.org/10.2337/db17-1281
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Complications

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    Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice
    Eleni Beli, Yuanqing Yan, Leni Moldovan, Cristiano P. Vieira, Ruli Gao, Yaqian Duan, Ram Prasad, Ashay Bhatwadekar, Fletcher A. White, Steven D. Townsend, Luisa Chan, Caitlin N. Ryan, Daniel Morton, Emil G. Moldovan, Fang-I Chu, Gavin Y. Oudit, Hartmut Derendorf, Luciano Adorini, Xiaoxin X. Wang, Carmella Evans-Molina, Raghavendra G. Mirmira, Michael E. Boulton, Mervin C. Yoder, Qiuhong Li, Moshe Levi, Julia V. Busik and Maria B. Grant
    Diabetes 2018 Sep; 67 (9): 1867-1879. https://doi.org/10.2337/db18-0158
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    Human Aldose Reductase Expression Prevents Atherosclerosis Regression in Diabetic Mice
    Chujun Yuan, Jiyuan Hu, Saj Parathath, Lisa Grauer, Courtney Blachford Cassella, Svetlana Bagdasarov, Ira J. Goldberg, Ravichandran Ramasamy and Edward A. Fisher
    Diabetes 2018 Sep; 67 (9): 1880-1891. https://doi.org/10.2337/db18-0156
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Genetics/Genomes/Proteomics/Metabolomics

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    Nonsynonymous Variants in PAX4 and GLP1R Are Associated With Type 2 Diabetes in an East Asian Population
    Soo Heon Kwak, Jeesoo Chae, Seungbok Lee, Sungkyoung Choi, Bo Kyung Koo, Ji Won Yoon, Jin-Ho Park, Belong Cho, Min Kyong Moon, Soo Lim, Young Min Cho, Sanghoon Moon, Young Jin Kim, Sohee Han, Mi Yeong Hwang, Yoon Shin Cho, Myung-Shik Lee, Hak C. Jang, Hyun Min Kang, Taesung Park, Nam H. Cho, Kyunga Kim, Jong-Il Kim and Kyong Soo Park
    Diabetes 2018 Sep; 67 (9): 1892-1902. https://doi.org/10.2337/db18-0361
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    The Common HNF1A Variant I27L Is a Modifier of Age at Diabetes Diagnosis in Individuals With HNF1A-MODY
    Jonathan M. Locke, Cécile Saint-Martin, Thomas W. Laver, Kashyap A. Patel, Andrew R. Wood, Seth A. Sharp, Sian Ellard, Christine Bellanné-Chantelot, Andrew T. Hattersley, Lorna W. Harries and Michael N. Weedon
    Diabetes 2018 Sep; 67 (9): 1903-1907. https://doi.org/10.2337/db18-0133
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Issues and Events

  • Open Access
    Issues and Events
    Diabetes 2018 Sep; 67 (9): 1908. https://doi.org/10.2337/db18-ie09
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Diabetes: 67 (9)

In this Issue

September 2018, 67(9)
  • Table of Contents
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